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Metaheps exhibit CYP P450 metabolism – induction by ethanol, phenytoin and dexamethasone

A Benesic, NL Rahm, S Ernst, E De Toni, M Escobar, V Gülberg, AL Gerbes · Zeitschrift für Gastroenterologie · Ausgabe 09/2009

DOI 10.1055/s-0029-1241358

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Autor:innenA Benesic, NL Rahm, S Ernst, E De Toni, M Escobar, V Gülberg, AL Gerbes
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben

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Aims: Considerable effort is aimed at the search for hepatocyte-like cells to use them in cell based therapies. Transformed peripheral monocytes have been described as a possible source of hepatocyte-like cells. In contrast to primary hepatocytes, monocytes are easy to isolate and available. Since primary hepatocytes loose functional CYP P450-metabolism after few days in culture, hepatocytoid cells with a stable and…

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A Benesic, NL Rahm, S Ernst, E De Toni, M Escobar, V Gülberg, AL Gerbes (2009) Metaheps exhibit CYP P450 metabolism – induction by ethanol, phenytoin and dexamethasone. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241358

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