CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
A functional promoter polymorphism in the chitinase-like protein gene (CH3L1) is associated with liver fibrosis in a FibroScan staged cohort
DOI 10.1055/s-0029-1241363
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Autor:innenF Grünhage, M Krawczyk, R Goebel, T Sauerbruch, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Cartilage glycoprotein-39 (YKL-40) is supposed to be involved in tissue remodelling and degradation of extracellular matrix. Recently a functional promoter variant (-131G>C) of the corresponding gene CH3L1 has been associated with advanced liver fibrosis in patients with chronic hepatitis C virus (HCV) infection (Berres et al. J Hepatol 2009;50:370–376). We aimed to verify this association in a cohort…
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Zitierempfehlung
F Grünhage, M Krawczyk, R Goebel, T Sauerbruch, F Lammert (2009) A functional promoter polymorphism in the chitinase-like protein gene (CH3L1) is associated with liver fibrosis in a FibroScan staged cohort. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241363
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