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Maintenance of virus-specific CD4+ T cell responses in chronic HCV infection in blood and liver identified by antigen-specific upregulation of CD154

N Semmo, M Müller, HC Spangenberg, N Kersting, T Altay, P Klenerman, HE Blum, R Thimme · Zeitschrift für Gastroenterologie · Ausgabe 09/2009

DOI 10.1055/s-0029-1241364

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Autor:innenN Semmo, M Müller, HC Spangenberg, N Kersting, T Altay, P Klenerman, HE Blum, R Thimme
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Virus-specific CD4+ T cells play a major role in HCV infection. Viral clearance is associated with vigorous and multispecific HCV-specific CD4+ T cell responses while chronic infection has been shown to be associated with weak or absent T cell immune responses. Most of these studies, however, have used functional assays to analyze virus-specific CD4+ T cell responses. Thus, the important question of wh…

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Zitierempfehlung

N Semmo, M Müller, HC Spangenberg, N Kersting, T Altay, P Klenerman, HE Blum, R Thimme (2009) Maintenance of virus-specific CD4+ T cell responses in chronic HCV infection in blood and liver identified by antigen-specific upregulation of CD154. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241364

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