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Transcription regulators of hepatic heme-oxygenase-1 gene expression in IL-6 knock out mice: Comparison of two different models of acute phase reaction

G Ahmad, P Ramadori, G Martius, G Ramadori · Zeitschrift für Gastroenterologie · Ausgabe 09/2009

DOI 10.1055/s-0029-1241551

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Autor:innenG Ahmad, P Ramadori, G Martius, G Ramadori
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben

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Introduction: Heme-oxygenase-1 (HO-1) has a crucial role in maintaining body iron metabolism during acute phase response (APR). Its expression is principally regulated at transcriptional level, and involves complex intracellular pathways in response to external stimuli. IL-6 is one of principle mediators of APR and most of its signalling pathways, including the ones regulating HO-1 gene expression, involve STAT3 act…

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G Ahmad, P Ramadori, G Martius, G Ramadori (2009) Transcription regulators of hepatic heme-oxygenase-1 gene expression in IL-6 knock out mice: Comparison of two different models of acute phase reaction. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241551

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