CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Galiellalactone inhibits pro-fibrogenic TGF-β effects in hepatic stellate cells
DOI 10.1055/s-0029-1241559
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Autor:innenJ Li, G Erkel, S Wölfel, C Meyer, J Dzieran, HL Weng, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Galiellalactone is a natural fungal metabolite isolated from the ascomycete Galiella rufa and was primary screened out as an inhibitor for IL-6/Stat3 signaling. It has been reported that galiellalactone induces apoptosis of phospho-Stat3 positive prostatic carcinoma cells and reduces mouse prostatic tumor xenograft growth. Recently we found that galiellalactone also inhibits the downstream signaling of T…
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Zitierempfehlung
J Li, G Erkel, S Wölfel, C Meyer, J Dzieran, HL Weng, S Dooley (2009) Galiellalactone inhibits pro-fibrogenic TGF-β effects in hepatic stellate cells. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241559
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