CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
BALB-Abcb4 mice lacking the hepatobiliary phospholipid transporter represent a potential model of hepatic osteodystrophy
DOI 10.1055/s-0029-1241569
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Nachweis in CareLit
Autor:innenK Hochrath, B Rathkolb, K Butuzova, W Hans, H Fuchs, V Gailus-Durner, E Wolf, M Hrabé de Angelis, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Metabolic bone disease occurring in patients with chronic cholestasis, known as hepatic osteodystrophy, is a potential complication of long-standing liver diseases. Abcb4 (Mdr2) knockout mice develop chronic cholangitis due to the lack of phosphatidylcholine from bile. This mouse model resembles progressive familial intrahepatic cholestasis type 3 in humans, which is caused by mutations of the orthologous phos…
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Zitierempfehlung
K Hochrath, B Rathkolb, K Butuzova, W Hans, H Fuchs, V Gailus-Durner, E Wolf, M Hrabé de Angelis, F Lammert (2009) BALB-Abcb4 mice lacking the hepatobiliary phospholipid transporter represent a potential model of hepatic osteodystrophy. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241569
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