CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepatic iron overload in patients with alcoholic liver disease is due to inadequate hepcidin induction
DOI 10.1055/s-0029-1241570
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Autor:innenG Millonig, GN Waite, M Muckenthaler, HK Seitz, S Mueller
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Alcoholic liver disease (ALD) leads to secondary iron overload in more than 50% patients that is considered a major factor in the progression of fibrosis and the development of hepatocellular carcinoma. Hepcidin is the major systemic iron sensor in mammals and typically induced under conditions of iron overload. Hepcidin blocks duodenal iron absorption and the release of iron by inflammatory cells. Suppressed…
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Zitierempfehlung
G Millonig, GN Waite, M Muckenthaler, HK Seitz, S Mueller (2009) Hepatic iron overload in patients with alcoholic liver disease is due to inadequate hepcidin induction. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241570
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