CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Growth speed plays a greater role than MMR status in determining the long-term survival of colon carcinoma cells treated with 5-FU
DOI 10.1055/s-0029-1241603
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Autor:innenB Choudhary, ML Hanski, M Zeitz, C Hanski
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Whether mutations in the hMLH1 gene, which is a component of the mismatch repair system, increase or decrease the sensitivity of colon carcinomas to 5-fluorouracil (5-FU) is a matter of controversy. We investigated the effect of growth speed and MMR status on long term survival of colon carcinoma cells after 5-FU treatment. Materials and methods: We used the HCT116 cell line which was either transfecte…
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Zitierempfehlung
B Choudhary, ML Hanski, M Zeitz, C Hanski (2009) Growth speed plays a greater role than MMR status in determining the long-term survival of colon carcinoma cells treated with 5-FU. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241603
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