CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Tumor-specific regulatory T cells suppress lytic granule release of adoptively transferred cytotoxic effector T cells and inhibit tumor rejection
DOI 10.1055/s-0029-1241604
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Nachweis in CareLit
Autor:innenC Bauer, F Marangoni, T Murooka, N Elpak, TR Mempel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Regulatory T cells (Treg) interfere with the rejection of malignant tumors through cytotoxic T cells (CTL), but it is not well characterized at which levels of the T cell response: (i) initial activation at the priming site, (ii) trafficking to tumors, (iii) survival and proliferation in the tumor stroma or (iv) the execution of effector function, Treg-mediated suppression of CTL function predominantly occurs.…
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Zitierempfehlung
C Bauer, F Marangoni, T Murooka, N Elpak, TR Mempel (2009) Tumor-specific regulatory T cells suppress lytic granule release of adoptively transferred cytotoxic effector T cells and inhibit tumor rejection. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241604
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