CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Dual selective antitumor effect of 5-azacytidine towards hepatocellular carcinoma cells
DOI 10.1055/s-0029-1241634
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Autor:innenS Venturelli, A Berger, T Weiland, M Zimmermann, I Smirnow, TS Weiss, A Königsrainer, M Gregor, UM Lauer, M Bitzer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction/aim: Epigenetic alterations play a major role during the development and maintenance of hepatocellular carcinoma (HCC) and a wide variety of other tumor entities. 5-azacytidine (5-aza-CR) and 5-aza-2'-deoxycytidine (5-aza-dC) are the most advanced drugs for a demethylating epigenetic therapy. Due to HCC resistance phenomena to chemotherapeutics or antitumor cytokines, such as the tumor necrosis factor-r…
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Zitierempfehlung
S Venturelli, A Berger, T Weiland, M Zimmermann, I Smirnow, TS Weiss, A Königsrainer, M Gregor, UM Lauer, M Bitzer (2009) Dual selective antitumor effect of 5-azacytidine towards hepatocellular carcinoma cells. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241634
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