CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Multityrosinkinase inhibition by sorafenib increases necrosis size after radiofrequency ablation in rat liver but activates compensatory growth signaling
DOI 10.1055/s-0029-1241635
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Nachweis in CareLit
Autor:innenJ Mertens, I Martin, P Frei, AH Mahnken, P Bruners, B Müllhaupt, A Geier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: The most widely employed local ablative treatment for unresectable HCC is radiofrequency ablation (RFA). The multityrosinkinase inhibitor sorafenib has shown survival benefits in pts at advanced stages and is currently under investigation for adjuvant treatment after HCC resection/ablation in human trials. Of potential concern, sorafenib may reduce liver regeneration after tissue ablation. Furthermore, antiang…
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Zitierempfehlung
J Mertens, I Martin, P Frei, AH Mahnken, P Bruners, B Müllhaupt, A Geier (2009) Multityrosinkinase inhibition by sorafenib increases necrosis size after radiofrequency ablation in rat liver but activates compensatory growth signaling. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241635
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