CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
ß-Catenin binding partners TCF4 and LEF1 differ with respect to their prognostic relevance in colorectal cancer
DOI 10.1055/s-0029-1242276
Bibliografische Angaben
Nachweis in CareLit
Autor:innenL Kriegl, D Horst, T Kirchner, A Jung
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe10/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: TCF4 and LEF-1 are members of the T-cell factor (TCF)/lymphoid enhancor factor (LEF-1) family acting as central transcription mediators in the Wnt signalling pathway. By binding to ß-Catenin in the nucleus they activate the expression of multiple target genes mediating proliferation and invasion. Previous studies mainly investigated the function of TCF4 as both factors are thought to have the same functional c…
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Zitierempfehlung
L Kriegl, D Horst, T Kirchner, A Jung (2009) ß-Catenin binding partners TCF4 and LEF1 differ with respect to their prognostic relevance in colorectal cancer. Zeitschrift für Gastroenterologie (10). https://doi.org/10.1055/s-0029-1242276
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