CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Frequency and Type of KRAS Mutations in Routine Diagnostic Analysis of Metastatic Colorectal Cancer
DOI 10.1055/s-0029-1242277
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Nachweis in CareLit
Autor:innenJ Neumann, E Zeindl-Eberhart, T Kirchner, A Jung
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe10/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Mutation analysis of the KRAS oncogene is now established as a predictive biomarker in colorectal cancer (CRC). Large prospective clinical trials showed that only CRCs with wild type KRAS respond to anti-epidermal growth factor receptor (EGFR) treatment. Therefore the mutation analysis is mandatory before treatment and reliable benchmarks of the frequency and types of KRAS-mutations have to be established for…
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Zitierempfehlung
J Neumann, E Zeindl-Eberhart, T Kirchner, A Jung (2009) Frequency and Type of KRAS Mutations in Routine Diagnostic Analysis of Metastatic Colorectal Cancer. Zeitschrift für Gastroenterologie (10). https://doi.org/10.1055/s-0029-1242277
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