CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
A common polymorphism in the ABCB11 gene encoding for the bile salt export pump is associated with advanced fibrosis in hepatitis C infection but not in fatty liver disease
DOI 10.1055/s-0029-1246329
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Autor:innenR Iwata, B Stieger, AK Daly, JC Mertens, P Frei, J Braun, A Vergopoulos, IV Martin, O Goetze, CP Day, B Müllhaupt, A Geier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: HCV-associated cirrhosis represents the main indication for liver transplantation in Western countries. Clinical factors influence the progression of fibrogenesis but cannot accurately predict the risk of cirrhosis. Bile acids (BA) contribute to hepatic stellate cell activation as a key event in fibrogenesis. Aim of this study was to investigate the role of BA and polymorphisms in BA level-regulating genes on…
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Zitierempfehlung
R Iwata, B Stieger, AK Daly, JC Mertens, P Frei, J Braun, A Vergopoulos, IV Martin, O Goetze, CP Day, B Müllhaupt, A Geier (2010) A common polymorphism in the ABCB11 gene encoding for the bile salt export pump is associated with advanced fibrosis in hepatitis C infection but not in fatty liver disease. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246329
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