CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The platelet-derived chemokine CXCL4 mediates experimental liver fibrosis and is associated with HCV and NASH induced fibrosis
DOI 10.1055/s-0029-1246330
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Autor:innenM Moreno Zaldivar, K Pauels, P Schmitz, ML Berres, R Weiskirchen, C Weber, C Trautwein, HE Wasmuth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Liver fibrosis is a major cause of morbidity and mortality worldwide. Platelets are involved in liver damage but the underlying molecular mechanisms remain elusive. We here investigate the platelet-derived chemokine CXCL4 as a molecular mediator of fibrotic liver damage. Methods: Serum concentrations and intrahepatic mRNA of CXCL4 were measured in patients with chronic liver diseases and mice after toxic liver…
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Zitierempfehlung
M Moreno Zaldivar, K Pauels, P Schmitz, ML Berres, R Weiskirchen, C Weber, C Trautwein, HE Wasmuth (2010) The platelet-derived chemokine CXCL4 mediates experimental liver fibrosis and is associated with HCV and NASH induced fibrosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246330
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