CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Silencing of liver-specific microRNA-122 aggravates acute but not chronic hepatotoxin-induced liver injury
DOI 10.1055/s-0029-1246331
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Autor:innenR Hall, I Adrian, K Hochrath, SN Weber, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hepatic inflammation and fibrogenesis represent complex responses to liver injury. Recent studies have identified micro RNAs as novel gene regulators. MiR-122 is a liver-specific micro RNA shown to be differentially expressed in hepatocellular carcinoma [1, 2]. To determine the role of miR-122 during experimental liver injury, we now studied the effects of an LNA-antimiR oligonucleotide (antimiR-122) that effectivel…
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Zitierempfehlung
R Hall, I Adrian, K Hochrath, SN Weber, F Lammert (2010) Silencing of liver-specific microRNA-122 aggravates acute but not chronic hepatotoxin-induced liver injury. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246331
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