CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Adiponectin downregulates connective tissue growth factor in hepatocytes and hepatic stellate cells
DOI 10.1055/s-0029-1246337
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Nachweis in CareLit
Autor:innenC Buechler, J Wanninger, M Neumeier, J Weigert, S Bauer, T Amann, TS Weiss, C Hellerbrand, A Schäffler, J Schoelmerich
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: Connective tissue growth factor (CTGF) is synthesized by hepatocytes and hepatic stellate cells (HSC). CTGF enhances TGFbeta signalling and is a central player in liver fibrosis. Adiponectin protects from liver fibrosis, and here, we analysed whether these hepatoprotective effects may partly be driven by an impact of this adipokine on CTGF synthesis. Methods: Adiponectin mediated suppression of CTGF was i…
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Zitierempfehlung
C Buechler, J Wanninger, M Neumeier, J Weigert, S Bauer, T Amann, TS Weiss, C Hellerbrand, A Schäffler, J Schoelmerich (2010) Adiponectin downregulates connective tissue growth factor in hepatocytes and hepatic stellate cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246337
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