CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
HGF/c-Met and IL-6/gp130 cooperatively regulate liver homeostasis and antibacterial signalling after bile-duct-ligation
DOI 10.1055/s-0029-1246346
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Nachweis in CareLit
Autor:innenA Giebeler, S Erschfeld, C Birchmeier, C Trautwein, KL Streetz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: HGF/c-Met and IL-6/gp130 play a crucial role as mediators of cellular survival and protection in the liver. Here we aimed to analyse its interactions on a cellular level in a model of acute cholestatic liver injury induced bile-duct-ligation (BDL). Material and Methods: Hepatocyte specific(Δhepa) conditional knockout mice (Cre-loxP system) for c-Met, gp130 and c-Met/gp130 were subjected to BDL. Results: Gp130Δ…
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Zitierempfehlung
A Giebeler, S Erschfeld, C Birchmeier, C Trautwein, KL Streetz (2010) HGF/c-Met and IL-6/gp130 cooperatively regulate liver homeostasis and antibacterial signalling after bile-duct-ligation. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246346
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