CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Endoglin is upregulated and counteracts profibrogenic responses in transdifferentiating hepatic stellate cells
DOI 10.1055/s-0029-1246359
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Autor:innenSK Meurer, L Tihaa, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: The main cellular source of extracellular matrix (ECM) in the fibrotic liver are myofibroblast-like cells (MFB) originating from mesenchymal hepatic stellate cells (HSC). In the fibrotic processes of kidney (mesangial cells), heart (cardiac fibroblasts) and dermis (dermal fibroblasts) it has been shown that the accessory receptor endoglin is upregulated in the respective profibrogenic cells and modulates fibro…
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Zitierempfehlung
SK Meurer, L Tihaa, R Weiskirchen (2010) Endoglin is upregulated and counteracts profibrogenic responses in transdifferentiating hepatic stellate cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246359
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