CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Caveolin-1 upregulation during hepatocyte transdifferentiation alters the TGF-beta response
DOI 10.1055/s-0029-1246360
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Nachweis in CareLit
Autor:innenC Meyer, Y Liu, J Dzieran, I Ilkavets, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Active TGF-beta receptors are internalized from the plasma membrane by two distinct endocytic routes. The clathrin dependent internalization route is considered to increase TGF-beta mediated Smad signaling, whereas the Caveolin-1 dependent endocytic route leads to receptor degradation and thus dampening of signaling. Noteworthy, recent work established Caveolin-1 as an active participant in TGF-beta signaling as con…
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Zitierempfehlung
C Meyer, Y Liu, J Dzieran, I Ilkavets, S Dooley (2010) Caveolin-1 upregulation during hepatocyte transdifferentiation alters the TGF-beta response. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246360
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