CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The multikinase-inhibitor Sorafenib prevents neoangiogenesis and higher NO production by the hepatic artery in CCl4-induced liver cirrhosis
DOI 10.1055/s-0029-1246377
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Nachweis in CareLit
Autor:innenA Zipprich, B Christ, T Seufferlein, M Dollinger
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The vascular resistance and the response of the hepatic artery (HA) to vasoconstrictors is decreased in cirrhosis due to neoangiogenesis, remodeling, and increased NO production (JHEP 2008;49: 739). Sorafenib is a multikinase-inhibitor that decreases neoangiogenesis. The aim of the study was to investigate the hemodynamic effect of the administration of Sorafenib during the development of cirrhosis on the HA. Method…
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Zitierempfehlung
A Zipprich, B Christ, T Seufferlein, M Dollinger (2010) The multikinase-inhibitor Sorafenib prevents neoangiogenesis and higher NO production by the hepatic artery in CCl4-induced liver cirrhosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246377
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