CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Analysis of a promoter polymorphism of the GLUT1 gene in patients with hepatocellular carcinoma
DOI 10.1055/s-0029-1246384
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Autor:innenT Amann, G Kirovski, A Bosserhoff, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
The glucose transporter isoform 1 (GLUT1) is a key rate-limiting factor in the transport and metabolism of glucose in cancer cells. Recently, we found that Glut1 expression is increased in hepatocellular carcinoma (HCC) and promotes tumorigenesis. Hypoxia further increased GLUT1 expression in HCC cells, and this induction was dependent on the activation of the transcription factor hypoxia-inducible factor (HIF)-1alp…
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Zitierempfehlung
T Amann, G Kirovski, A Bosserhoff, C Hellerbrand (2010) Analysis of a promoter polymorphism of the GLUT1 gene in patients with hepatocellular carcinoma. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246384
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