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Proteasome inhibition during oncolytic infection improves antitumoral immunity and inhibits metastatic growth of HCC

B Boozari, B Mundt, N Woller, E Gürlevik, P Schache, M Manns, S Kubicka, F Kühnel · Zeitschrift für Gastroenterologie · Ausgabe 01/2010

DOI 10.1055/s-0029-1246388

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Autor:innenB Boozari, B Mundt, N Woller, E Gürlevik, P Schache, M Manns, S Kubicka, F Kühnel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Infection of a dying cell by a pathogen dictates the immune response against intracellular antigens, but the impact of tumor cell death during oncolytic viral infection on the induction of antitumoral immunity is unknown. Recently, ER-stress due to disruption of the unfolded-protein-response (UPR) has been implicated in the bypass of immune tolerance mechanisms. Since viruses and proteasome inhibitors both induce ac…

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B Boozari, B Mundt, N Woller, E Gürlevik, P Schache, M Manns, S Kubicka, F Kühnel (2010) Proteasome inhibition during oncolytic infection improves antitumoral immunity and inhibits metastatic growth of HCC. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246388

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