CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Smad7 and TGF-β signaling – a double edged sword in liver tumorigenesis
DOI 10.1055/s-0029-1246398
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Nachweis in CareLit
Autor:innenJ Dzieran, J Fabian, B Bauche, A Tannapfel, S Dooley, NM Meindl-Beinker
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hepatocellular carcinoma (HCC) is one of the most common and deadliest cancers worldwide. TGF-β is a driver of chronic liver disease progression, which eventually ends in HCC. TGF-β, a tumor suppressor in cancer development, exerts tumor supporting characteristics during cancer progression. However, TGF-β signaling related mutations regularly occurring in different cancers are comparably rare in HCC. Here we analyze…
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Zitierempfehlung
J Dzieran, J Fabian, B Bauche, A Tannapfel, S Dooley, NM Meindl-Beinker (2010) Smad7 and TGF-β signaling – a double edged sword in liver tumorigenesis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246398
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