CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Impaired intestinal defensin production enhances bacterial translocation and subsequently increases hepatic inflammation and fibrogenesis in an experimental NASH model–a new second hit
DOI 10.1055/s-0029-1246402
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Nachweis in CareLit
Autor:innenE Gäbele, K Dostert, R Wiest, J Schoelmerich, C Hellerbrand, F Obermeier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Increased intestinal permeability and bacterial overgrowth and are pathophysiological factors of NASH. Recently, we developed a new experimental setting combining a dietary NASH model with a model of chronic colitis, induced by application of dextran sulphate sodium (DSS), in order to study the liver-gut axis. The aim of the current study was to investigate the mechanism of bacterial translocation in our model…
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Zitierempfehlung
E Gäbele, K Dostert, R Wiest, J Schoelmerich, C Hellerbrand, F Obermeier (2010) Impaired intestinal defensin production enhances bacterial translocation and subsequently increases hepatic inflammation and fibrogenesis in an experimental NASH model–a new second hit. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246402
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