CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
FOXO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by Resveratrol
DOI 10.1055/s-0029-1246415
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Nachweis in CareLit
Autor:innenT Kietzmann, G Ganjam, E Dimova
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Resveratrol, a polyphenol derived from grapes, exerts important effects on glucose and lipid metabolism, yet detailed mechanisms mediating these effects remain unknown. The liver plays a central role in energy homeostasis and glucokinase (GK) is a key enzyme involved in glucose utilization. Resveratrol activates sirtuin 1 (SIRT1) which promotes deacetylation of the forkhead transcription factor FoxO1. Previously, we…
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Zitierempfehlung
T Kietzmann, G Ganjam, E Dimova (2010) FOXO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by Resveratrol. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246415
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