CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of hepatocellular carcinoma
DOI 10.1055/s-0029-1246416
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Autor:innenG Kirovski, A Stevens, K Dettmer, A Bosserhoff, P Oefner, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Recently, we have shown that downregulation of methylthioadenosine phosphorylase (MTAP) in hepatocellular carcinoma (HCC) cells is caused by promoter-hypermethylation and induces proliferation and resistance against cytokines. The aim of this study was to expanded this analysis to human HCC tissue und to investigate the molecular mechanisms underlying the tumor-promoting effect of MTAP. Methods and Res…
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Zitierempfehlung
G Kirovski, A Stevens, K Dettmer, A Bosserhoff, P Oefner, C Hellerbrand (2010) Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of hepatocellular carcinoma. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246416
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