CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Exploring the diversity of ways to overcome TRAIL resistance in HCC: contribution of survival signaling, chemotherapeutical drugs and antiapoptotic BCL-2 proteins
DOI 10.1055/s-0029-1246420
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Autor:innenBC Köhler, T Urbanik, B Vick, RJ Boger, S Heeger, PR Galle, M Schuchmann, H Schulze-Bergkamen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aim: In this study we analysed ways to overcome resistance of hepatocellular carcinoma (HCC) cells towards apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). In particular, the effect of treatment with recombinant TRAIL or agonistic TRAIL antibodies in combination with chemotherapeutic drugs, specific kinase inhibitors as well as the commitment of antiapoptotic BCL-2 proteins was i…
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Zitierempfehlung
BC Köhler, T Urbanik, B Vick, RJ Boger, S Heeger, PR Galle, M Schuchmann, H Schulze-Bergkamen (2010) Exploring the diversity of ways to overcome TRAIL resistance in HCC: contribution of survival signaling, chemotherapeutical drugs and antiapoptotic BCL-2 proteins. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246420
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