CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Acyl-CoA synthetase 5 induces apoptosis sensitisation in human hepatocytes by channelling Acyl-CoAs into sphingolipid metabolism
DOI 10.1055/s-0029-1246445
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Autor:innenA Reinartz, A Leue, R Knuechel-Clarke, C Liedtke, AH Merrill, N Gassler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
In the pathogenesis of nonalcoholic fatty liver disease, accumulation of lipids in hepatocytes and hepatocyte apoptosis are strongly implicated in disease progression from the potentially reversible condition of steatosis to severe acute and chronic liver injury. Acyl-CoA synthetase 5 (ACSL5), a member of the ACSL gene family that catalyzes the activation of long-chain fatty acids for lipid biosynthesis, is the only…
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Zitierempfehlung
A Reinartz, A Leue, R Knuechel-Clarke, C Liedtke, AH Merrill, N Gassler (2010) Acyl-CoA synthetase 5 induces apoptosis sensitisation in human hepatocytes by channelling Acyl-CoAs into sphingolipid metabolism. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246445
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