CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The p53 family target gene signature is of prognostic relevance in hepatocellular carcinoma
DOI 10.1055/s-0029-1246451
Bibliografische Angaben
Nachweis in CareLit
Autor:innenF Staib, H Mundt, A Koch, M Krupp, PR Galle, W Stremmel, A Teufel, M Müller
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We have established that p53 and TAp63/TAp73 play a relevant role in hepatocarcinogenesis and in the therapeutic response of human hepatocellular carcinoma (HCC). Like p53, TAp63 and TAp73 activate genes that play roles in different steps of the apoptosis program. Accordingly, the therapeutic response/prognosis is not determined by p53 alone, but by the interactions between the different p53 family members. In order…
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Zitierempfehlung
F Staib, H Mundt, A Koch, M Krupp, PR Galle, W Stremmel, A Teufel, M Müller (2010) The p53 family target gene signature is of prognostic relevance in hepatocellular carcinoma. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246451
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