CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hippo pathway-independent nuclear export of the transcriptional activator YAP regulates proliferation and migration in HCC cells
DOI 10.1055/s-0029-1246461
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Autor:innenDF Tschaharganeh, M Malz, P Schirmacher, K Breuhahn
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: The Hippo pathway is a central regulator of organ size in different organisms. Hippo signalling is regulated by direct cell-cell interaction and contact inhibition, leading to phosphorylation and cytoplasmic retention of the transcriptional co-activator YAP (yes-associated protein). Because most human cancer cells become refractory to contact inhibition, it was suggested that this pathway and especially the nu…
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Zitierempfehlung
DF Tschaharganeh, M Malz, P Schirmacher, K Breuhahn (2010) Hippo pathway-independent nuclear export of the transcriptional activator YAP regulates proliferation and migration in HCC cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246461
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