CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Potent antifibrotic activity of mTOR inhibitors Sirolimus and Everolimus but not of Cyclosporine A and Tacrolimus in experimental liver fibrosis
DOI 10.1055/s-0029-1246484
Bibliografische Angaben
Nachweis in CareLit
Autor:innenE Patsenker, M Ledermann, H Saegesser, V Schneider, F Stickel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Recurrence of chronic hepatitis C (CHC) and progressive fibrosis in liver transplants impairs graft and patient survival. Recent evidence suggests that calcineurin inhibitors such as cyclosporine A exert antiviral effects, while others, such as sirolimus, may have antifibrotic properties. However, it is unclear whether the choice of immunosuppressant affects the course liver graft fibrosis. The aim of the pres…
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Zitierempfehlung
E Patsenker, M Ledermann, H Saegesser, V Schneider, F Stickel (2010) Potent antifibrotic activity of mTOR inhibitors Sirolimus and Everolimus but not of Cyclosporine A and Tacrolimus in experimental liver fibrosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246484
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