CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The Membrane Anchor of GB virus B Nonstructural Protein 5B Can Substitute the Hepatitis C Virus NS5B Transmembrane Domain: Implications for a Conserved Protein Interaction Site
DOI 10.1055/s-0029-1246500
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Autor:innenV Brass, J Gouttenoire, A Wahl, Z Pal, HE Blum, F Penin, D Moradpour
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background and aim: Hepatitis C virus (HCV) nonstructural proteins form a membrane-associated replication complex. HCV Nonstructural protein 5B (NS5B), the viral RNA-dependent RNA polymerase (RdRp), is a tail-anchored protein with a highly conserved C-terminal transmembrane domain (TMD) that is required for the assembly of a functional replication complex. The aim of this study was to further validate the function o…
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Zitierempfehlung
V Brass, J Gouttenoire, A Wahl, Z Pal, HE Blum, F Penin, D Moradpour (2010) The Membrane Anchor of GB virus B Nonstructural Protein 5B Can Substitute the Hepatitis C Virus NS5B Transmembrane Domain: Implications for a Conserved Protein Interaction Site. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246500
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