CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Conversion of naïve T Cells into regulatory T Cells after tolerance induction in the murine liver
DOI 10.1055/s-0029-1246504
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Autor:innenB Claass, A Erhardt, G Tiegs
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Recently, we have demonstrated that sublethal doses of concanavalin A (ConA) induce tolerance towards ConA hepatitis in mice within one week. Tolerance is mediated by IL-10 producing regulatory T cells (Tregs). In vivo and in vitro data suggested that highly suppressive ConA-primed Foxp3+ Tregs might convert naïve CD4+ T cells into immunosuppressive Foxp3+ T cells. Hence, this study was intended to ide…
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Zitierempfehlung
B Claass, A Erhardt, G Tiegs (2010) Conversion of naïve T Cells into regulatory T Cells after tolerance induction in the murine liver. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246504
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