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Autoantibodies to asialoglycoprotein receptor (ASGPR) measured by a novel ELISA–revival of a disease-activity marker in autoimmune hepatitis (AIH)

K Conrad, D Roggenbuck, E Feist, G Hausdorf, T Buettner, CP Berg, R Klein · Zeitschrift für Gastroenterologie · Ausgabe 01/2010

DOI 10.1055/s-0029-1246505

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Autor:innenK Conrad, D Roggenbuck, E Feist, G Hausdorf, T Buettner, CP Berg, R Klein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Aims: Aim of the study was to develop a novel solid-phase immunoassay for the detection of anti-ASGPR IgG demonstrated to correlate with disease activity in AIH. However, due to the fragility of this liver-specific autoantigen, no standardised immunoassay has been available until now. Methods: ASGPR was purified by affinity chromatography on galactose-Sepharose from rabbit liver and used for standardised detection b…

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K Conrad, D Roggenbuck, E Feist, G Hausdorf, T Buettner, CP Berg, R Klein (2010) Autoantibodies to asialoglycoprotein receptor (ASGPR) measured by a novel ELISA–revival of a disease-activity marker in autoimmune hepatitis (AIH). Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246505

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