CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Differences in the source sequence of two HCV genotype 1b outbreaks within immunodominant CD8 epitopes are associated with differential outcome
DOI 10.1055/s-0029-1246509
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Autor:innenS Giugliano, M Ruhl, C Neumann-Haefelin, M Wiese, R Thimme, M Roggendorf, U Spengler, J Nattermann, J Timm
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Distinct HLA-class I alleles have a differential impact on the outcome of HCV infection. In the Irish Anti-D cohort HLA-B27 was associated with spontaneous control and HLA-B8 with viral persistence. Although the protective effect of HLA-B27 was confirmed in other cohorts, discrepant results have been obtained for HLA-B8. The aim of this study is to determine the role of sequence differences in the source virus…
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Zitierempfehlung
S Giugliano, M Ruhl, C Neumann-Haefelin, M Wiese, R Thimme, M Roggendorf, U Spengler, J Nattermann, J Timm (2010) Differences in the source sequence of two HCV genotype 1b outbreaks within immunodominant CD8 epitopes are associated with differential outcome. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246509
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