CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Increased bile acid levels reduce antiviral treatment response in genotype 2/3 hepatitis C patients whereas gamma-GT selectively predicts SVR in genotype 1
DOI 10.1055/s-0029-1246512
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Autor:innenR Iwata, B Stieger, JC Mertens, O Goetze, IV Martin, K Sabrane, A Vergopoulos, J Braun, B Müllhaupt, A Geier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: The likelihood of achieving a SVR to antiviral therapy depends on both viral and host characteristics. Recently, in vitro studies demonstrated that bile acids (BA) upregulate HCV replication and interfere with IFN effects. Aims: To investigate the influence of BA concentrations and a frequent ABCB11 transporter SNP (associated with lower BSEP expression) on viral load and SVR in HCV pts. Methods: N=198 pts wit…
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Zitierempfehlung
R Iwata, B Stieger, JC Mertens, O Goetze, IV Martin, K Sabrane, A Vergopoulos, J Braun, B Müllhaupt, A Geier (2010) Increased bile acid levels reduce antiviral treatment response in genotype 2/3 hepatitis C patients whereas gamma-GT selectively predicts SVR in genotype 1. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246512
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