CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
HBsAg is a potent suppressor of Toll-like receptor mediated innate and adaptive immune responses in liver cells and PBMC
DOI 10.1055/s-0029-1246513
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Autor:innenM Jiang, M Trippler, R Bröring, J Wu, M Roggendorf, G Gerken, M Lu, JF Schlaak
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: We have previously shown that HBV can suppress the innate immune system of the murine liver. However, it is not clear whether HBV may also interfere with human innate immunity and the adaptive immune system. Methods: Murine hepatocytes and NPC (Kupffer cells, KC and sinusoidal endothelial cells, LSEC) were stimulated by TLR3 and -4 ligands in the presence or absence of HBsAg. Total RNA was isolated 6h after st…
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Zitierempfehlung
M Jiang, M Trippler, R Bröring, J Wu, M Roggendorf, G Gerken, M Lu, JF Schlaak (2010) HBsAg is a potent suppressor of Toll-like receptor mediated innate and adaptive immune responses in liver cells and PBMC. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246513
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