CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The Heme oxygenase 1 product Biliverdin interferes with HCV replication by increasing anti-viral interferon response
DOI 10.1055/s-0029-1246532
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Autor:innenG Sass, E Lehmann, WH El-Tantawy, M Ocker, R Bartenschlager, V Lohmann, S Hashemolhosseini, G Tiegs
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background and Aims: The anti-apoptotic and hepatoprotective protein heme oxygenase-1 (HO-1) has been shown to interfere with replication of viruses, e.g. hepatitis B virus (HBV) and hepatitis C virus (HCV). Since HO-1 degrades heme to carbon monoxide (CO), iron and biliverdin, we investigated the effect of each product on HCV replication in vitro. Methods: HO-1 was induced using cobalt-protoporphyrin-IX (CoPP). Huh…
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Zitierempfehlung
G Sass, E Lehmann, WH El-Tantawy, M Ocker, R Bartenschlager, V Lohmann, S Hashemolhosseini, G Tiegs (2010) The Heme oxygenase 1 product Biliverdin interferes with HCV replication by increasing anti-viral interferon response. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246532
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