CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The strength of the Fas ligand signal determines whether hepatocytes act as type-1 or type-2 cells in murine livers
DOI 10.1055/s-0029-1246536
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Autor:innenS Schüngel, LE Buitrago-Molina, P Nalapareddy, M Lebofsky, A Gross, M Manns, H Jaeschke, A Vogel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Apoptosis induced by Fas activation has been implicated in a variety of liver diseases.1,2 Binding of the FasL to its receptor triggers intracellular activation of caspase-8.3–6 In type I cells caspase-8 activates the effector caspases which suffices to kill the cell. In type II cells caspase-8 requires a mitochondria-amplification loop to induce cell death.7,8 Bid was identified to mediate the apoptotic signal from…
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Zitierempfehlung
S Schüngel, LE Buitrago-Molina, P Nalapareddy, M Lebofsky, A Gross, M Manns, H Jaeschke, A Vogel (2010) The strength of the Fas ligand signal determines whether hepatocytes act as type-1 or type-2 cells in murine livers. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246536
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