CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Endothelial cell cross-presentation initiates TNFα-dependent CD8 T cell immunity against virus-infected hepatocytes
DOI 10.1055/s-0029-1246537
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Nachweis in CareLit
Autor:innenD Stabenow, K Gärtner, M Odenthal, M Krönke, U Protzer, HP Dienes, P Knolle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Viral infections in the liver are generally considered to be cleared in an MHC class I restricted killing of hepatocytes by CD8+ T cells. We believe that direct recognition of infected hepatocytes is an inefficient way and show that there exist an additional, more potent, mechanism. Using a tie2-H2-Kb transgenic mouse, where antigen is solely presented in the context of the MHC class I molecule H2-Kb on liver sinuso…
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Zitierempfehlung
D Stabenow, K Gärtner, M Odenthal, M Krönke, U Protzer, HP Dienes, P Knolle (2010) Endothelial cell cross-presentation initiates TNFα-dependent CD8 T cell immunity against virus-infected hepatocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1246537
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