CareLit · DOI-Nachweis · Pneumologie
Mycobacteria-induced granuloma necrosis depends on IRF-1
DOI 10.1055/s-0029-1247899
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Aly, J Mages, N Reiling, U Kalinke, T Decker, R Lang, S Ehlers
ZeitschriftPneumologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
In a mouse model of mycobacteria-induced immunopathology, wildtype C57BL/6 (WT) and IFNαβ-receptor-KO mice developed circumscript, centrally necrotizing granulomatous lesions in response to aerosol infection with M. avium, whereas mice deficient in the IFN-γ-receptor, STAT-1 or IRF-1 did not exhibit granuloma necrosis. Comparative, microarray-based gene expression analysis in the lungs of infected WT, IFN-γ-KO and I…
Zitieren
Zitierempfehlung
S Aly, J Mages, N Reiling, U Kalinke, T Decker, R Lang, S Ehlers (2010) Mycobacteria-induced granuloma necrosis depends on IRF-1. Pneumologie (01). https://doi.org/10.1055/s-0029-1247899
Mit CareLit weiterarbeiten