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Expression and functionality of proteinase-activated receptors (PARs) on primary human lung mast cells

O Ghulam, F Petersen, B Kasper, E Brandt · Pneumologie · Ausgabe 01/2010

DOI 10.1055/s-0029-1247914

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Autor:innenO Ghulam, F Petersen, B Kasper, E Brandt
ZeitschriftPneumologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben

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Introduction: Mast cell (MC) activation is known to promote anaphylactic reactions as well as the development of allergic and non-allergic inflammatory diseases. Apart from reacting to cross-linking of IgE-receptors by allergen, MC can be activated through a variety of alternative mechanisms. There is initial evidence that also proteinase-activated receptors (PARs) could have a role. PARs belong to the G protein-cou…

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O Ghulam, F Petersen, B Kasper, E Brandt (2010) Expression and functionality of proteinase-activated receptors (PARs) on primary human lung mast cells. Pneumologie (01). https://doi.org/10.1055/s-0029-1247914

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