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Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudates macrophage recruitment in response to pneumococcal lung infection

W Herbold, R Maus, I Hahn, N Ding, M Mack, J Reutershan, T Welte, UA Maus · Pneumologie · Ausgabe 01/2010

DOI 10.1055/s-0029-1247920

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Autor:innenW Herbold, R Maus, I Hahn, N Ding, M Mack, J Reutershan, T Welte, UA Maus
ZeitschriftPneumologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Aims: Sustained neutrophilic infiltration is known to contribute to organ damage, such as acute lung injury. CXC chemokine receptor 2 (CXCR2) is the major receptor regulating inflammatory neutrophil recruitment in acute and chronic inflamed tissues. Whether the abundant neutrophil recruitment observed in severe pneumonia is essential for protective immunity against Streptococcus pneumoniae is poorly defined. Results…

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W Herbold, R Maus, I Hahn, N Ding, M Mack, J Reutershan, T Welte, UA Maus (2010) Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudates macrophage recruitment in response to pneumococcal lung infection. Pneumologie (01). https://doi.org/10.1055/s-0029-1247920

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