CareLit · DOI-Nachweis · Pneumologie
TRAIL induction in lung macrophages is IFN-ß-dependent and results in alveolar epithelial apoptosis in IV pneumonia
DOI 10.1055/s-0029-1247921
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Högner, L Cakarova, S Pleschka, W Seeger, J Lohmeyer, S Herold
ZeitschriftPneumologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Influenza virus (IV) pneumonia is characterized by rapid progression to lung failure and high mortality. Although lung macrophages have been attributed a significant role in the host defense towards IV, they are as well contributing to alveolar epithelial cell damage and lung barrier dysfunction during IV pneumonia by the release pro-apoptotic mediators such as TNF-related apoptosis-inducing ligand (TR…
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Zitierempfehlung
K Högner, L Cakarova, S Pleschka, W Seeger, J Lohmeyer, S Herold (2010) TRAIL induction in lung macrophages is IFN-ß-dependent and results in alveolar epithelial apoptosis in IV pneumonia. Pneumologie (01). https://doi.org/10.1055/s-0029-1247921
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