CareLit · DOI-Nachweis · Pneumologie
ABCA3 mutations influence the stress level and immunological function of lung epithelial A549 cells
DOI 10.1055/s-0029-1247924
Bibliografische Angaben
Nachweis in CareLit
Autor:innenE Kaltenborn, L Fragnet, KK Konzelmann, N Weichert, M Griese, S Moslavac
ZeitschriftPneumologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Einleitung: ABCA3 is an ABC-transporter in the outer membrane of lamellar bodies (LBs) in alveolar epithelial type II cells (ATII) involved in the surfactant lipid transport. Mutations in the ABCA3 gene have been associated with genetic interstitial lung disease (ILD). Next to being essential for surfactant secretion, ATII are an active part of the lung immunological system and involved in lung repair. We investigat…
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Zitierempfehlung
E Kaltenborn, L Fragnet, KK Konzelmann, N Weichert, M Griese, S Moslavac (2010) ABCA3 mutations influence the stress level and immunological function of lung epithelial A549 cells. Pneumologie (01). https://doi.org/10.1055/s-0029-1247924
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