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Response of Alveolar Epithelial Cells exposed to Zinc Oxide Nanoparticles: Comparison of Exposure under Air-liquid Interface or Submerged Conditions

AG Lenz, E Karg, E Bitterle, KL Maier, O Schmid, T Stoeger · Pneumologie · Ausgabe 01/2010

DOI 10.1055/s-0029-1247931

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Autor:innenAG Lenz, E Karg, E Bitterle, KL Maier, O Schmid, T Stoeger
ZeitschriftPneumologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Inhalation of zinc oxide (ZnO) nanoparticles (NPs) has been associated with pro-inflammatory responses in the lung. However, dosimetric uncertainties limit the relevance of exposures conducted under submerged culture conditions and especially for airborne NPs, cell exposure at the air-liquid-interface (ALI) is more realistic. Methods: A549 cells were exposed to ZnO NPs under both submerged and ALI cult…

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AG Lenz, E Karg, E Bitterle, KL Maier, O Schmid, T Stoeger (2010) Response of Alveolar Epithelial Cells exposed to Zinc Oxide Nanoparticles: Comparison of Exposure under Air-liquid Interface or Submerged Conditions. Pneumologie (01). https://doi.org/10.1055/s-0029-1247931

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