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A novel, easy-to-use cell exposure system (ALICE) for controlled pharmaco-toxicological studies with liquids at the air-liquid interface

AG Lenz, B Lentner, V Dittrich, C Brandenberger, B Rothen-Rutishauser, H Schulz, GA Ferron, E Karg, O Schmid · Pneumologie · Ausgabe 01/2010

DOI 10.1055/s-0029-1247932

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Autor:innenAG Lenz, B Lentner, V Dittrich, C Brandenberger, B Rothen-Rutishauser, H Schulz, GA Ferron, E Karg, O Schmid
ZeitschriftPneumologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Typically, pharmacological and toxicological in vitro cell studies are performed under submerged cell conditions, i.e. the substance of interest is mixed directly into the cell culture medium. However for cell systems located at the air-liquid interface (e.g. lung epithelium, skin), controlled cell exposures at the air-liquid interface are more realistic. Methods: Here we present a technically simple,…

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AG Lenz, B Lentner, V Dittrich, C Brandenberger, B Rothen-Rutishauser, H Schulz, GA Ferron, E Karg, O Schmid (2010) A novel, easy-to-use cell exposure system (ALICE) for controlled pharmaco-toxicological studies with liquids at the air-liquid interface. Pneumologie (01). https://doi.org/10.1055/s-0029-1247932

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