CareLit · DOI-Nachweis · Pneumologie
Dickkopf proteins influence lung epithelial cell proliferation in idiopathic pulmonary fibrosis
DOI 10.1055/s-0029-1247942
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Nachweis in CareLit
Autor:innenEM Pfaff, S Becker, A Guenther, O Eickelberg, M Königshoff
ZeitschriftPneumologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with unknown pathogenesis. The WNT/β-catenin pathway has recently been reported to be operative in epithelial cells in IPF. Dickkopf (DKK) proteins are known to regulate WNT signaling via interaction with Kremen (KRM) receptors, yet their expression and role in the adult lung and in IPF has not been addressed. Methods: We analyzed th…
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Zitierempfehlung
EM Pfaff, S Becker, A Guenther, O Eickelberg, M Königshoff (2010) Dickkopf proteins influence lung epithelial cell proliferation in idiopathic pulmonary fibrosis. Pneumologie (01). https://doi.org/10.1055/s-0029-1247942
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