CareLit · DOI-Nachweis · Pneumologie
Increased generation of reactive oxygen species in pulmonary arterial smooth muscle cells from monocrotaline-treated rats
DOI 10.1055/s-0029-1247956
Bibliografische Angaben
Nachweis in CareLit
Autor:innenF Veit, M Roth, B Egemnazarov, M Seimetz, HA Ghofrani, W Seeger, RT Schermuly, F Grimminger, N Weissmann
ZeitschriftPneumologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Chronic alveolar hypoxia induces pulmonary hypertension (PH), concomitant with pulmonary vascular remodeling. Reactive oxygen species (ROS) are thought to play a major role in this process. Our recent findings suggest that ROS production by the NADPH-oxidase (NOX) subunits play an important role in this remodeling process. Objectives: We investigated whether similar mechanisms are active for non-hypoxia i…
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Zitierempfehlung
F Veit, M Roth, B Egemnazarov, M Seimetz, HA Ghofrani, W Seeger, RT Schermuly, F Grimminger, N Weissmann (2010) Increased generation of reactive oxygen species in pulmonary arterial smooth muscle cells from monocrotaline-treated rats. Pneumologie (01). https://doi.org/10.1055/s-0029-1247956
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